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Flash facts TOXINS AND THEIR ACTION Cholera toxin enters | USMLE FACTS (step1) channel

Flash facts
TOXINS AND THEIR ACTION

Cholera toxin
enters the cell and constitutively activates the Gs protein

Shiga toxin
(seen in shigellosis) cleaves host cell rRNA (Blocking 60S)

Bacillus anthracis
toxin directly acts as an adenylate cyclase

Diphtheria toxin
and exotoxin A of Pseudomonas inactivate elongation factor 2

Bordetella pertussis exotoxin
permanently inactivates Gi protein